Male birth control pill could be around the corner

Male birth control pill could be around the corner

A male pill could be on the horizon after early trials showed a once-daily tablet was safe and appeared to work, according to researchers.

According to a report from the Telegraph, the pill contains a drug known as dimethandrolone undecanoate (DMAU), which differs from other similar drugs before it due to the inclusion of a long-chain fatty acid that allows it to metabolize at a slower pace, meaning it should only be taken once a day instead of twice.

"And 60 to 80 percent of men surveyed in such studies say if there was a reversible contraceptive available, they would be very interested in using it".

Eighty-three men aged 18 to 50 completed the study, which tested the effects of different doses (100, 200, and 400 milligrams) and formulations inside capsules (castor oil and powder) of DMAU.

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Dr Page said longer term studies are now underway to confirm that when taken every day, DMAU blocks sperm production. It also required two doses a day."It's hard enough to do not forget to take a pill once a day", Page said.

"Despite having low levels of circulating testosterone, very few subjects reported symptoms consistent with testosterone deficiency or excess", Stephanie Page explained. Unlike other forms of oral testosterone, which classically are cleared from the body quickly, this compound contains a specific long-chain fatty acid that slows this clearance making it a ideal "once-a-day" pill.

The researchers are now conducting longer-term studies on the efficacy and safety of DMAU.

In a nutshell (sorry, couldn't resist), the pill lowers sperm hormones while not altering testosterone levels.

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The pill was also well tolerated, with groups taking DMAU experiencing slight weight gain and decreases in "good" cholesterol levels, but these effects were mild, Dr. Page said. However, it was noted that the pill needed to be taken with food in order to work successfully.

She added: 'These promising results are unprecedented in the development of a prototype male pill'. This is why another male contraceptive just straight up blocks sperm; it only takes one to cause pregnancy, after all. Maybe the study that begins in April will present us encouraging findings as well as the one presented at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, on Sunday. DMAU "does have the promise of blocking sperm production", Courgi said.

The development of a male contraceptive pill has over the years been affected by side-effects on fertility, birth defects and libido. The pills need to be taken with food to be effective, she said.

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